How do cells take up the correct substrates in endocytosis? A、They don’t, they randomly take up substrates and secrete what they don’t need. B、The clathrin protein recognizes the correct substrate and will concentrate it in vesicles. C、The adaptin protein will recognize the correct substrate and concentrate it in vesicles. D、A receptor, specific for the substrate, will concentrate it into endocytic vesicles. E、None of the above.